Overview

For the symptomatic treatment of acute diarrhoea, in adults and children 12 years and over. For the symptomatic treatment of acute episodes of diarrhoea associated with Irritable Bowel Syndrome in adults aged 18 years and over following initial diagnosis by a doctor.

Adults and children over 12:

• 2 capsules (4 mg) initially, followed by 1 capsule (2mg) after every loose stool
• The usual dose is 3-4 capsules (6 mg – 8 mg) a day. The total daily dose should not exceed 6 capsules (12 mg)

Adults aged 18 and over:

• Two capsules (4 mg) to be taken initially, followed by 1 capsule (2mg) after every loose stool, or as previously advised by your doctor
• The maximum daily dose should not exceed 6 capsules (12mg)

Paediatric population:

• Loperamide hydrochloride is contraindicated in children less than 12 years of age

Elderly:

• No dose adjustment is required for the elderly.

Renal Impairment:

• No dose adjustment is required for patients with renal impairment.

Hepatic Impairment:

• Although no pharmacokinetic data are available in patients with hepatic impairment, loperamide hydrochloride should be used with caution in such patients because of reduced first-pass metabolism (see section 4.4 Special warnings and precautions for use).